i an onto alot of animating problems when i moved certain bones, and some times not,
theres been times when i moved the elbow or teh hand and it made the foot twist, or the spine twist, or both, then i move it back and its fine,
but theres also cases where ive had to reposition the legs and arms entirely and it worked perfectly,
i havent done it enough to determine what causes it, but i try to keep the skeleton at default most times