'Spider Carnage was the ultimate evil according to madam web.
All together, spiderman was his own worst enemey, nothing was more evil then when he transformed in a spider. Carnage and venom were allright, but their weakness to sound made them a bit less cool imho... I liked the vampire saga, forgot the name of the vampire queen but she was a pretty good vilian too..
I'll vote for carnage since it's most close to spider carnage.
Oh something else, kingpin should be up there too... not that he was the best, but he played an important role
grtz Naz