Even though I haven't really warmed up to it (via the multiplayer beta), I'm still kinda looking forward to DoW 2.
Also, Empire: Total War, and (though I don't recall when it's coming out) Ghostbusters.
The big one? Dragon Age: Origins. I've been waiting for a decent, hard-core RPG (a la BG2) to come around again for some time. I hope this one doesn't disappoint!
That's about it for games coming up on the immediate horizon. Perhaps something coming out in the latter half of 2009 will pique my interest. For now, though, it looks to be a dull year for me.