Well, I just got to disc 2. So far, this game is pretty fun, but it feels different.. more like a shooter RPG I guess? I'm not really a fan of how the guns work in this game, I personally prefer the old system (overheating), but the new weapons are quite awesome. I really like the new Normandy, definitely more awesome compared to the old one. A bit disappointed that you can't get your whole crew back (I'm not sure if you actually do, I'm pretty early in the game I guess ;p), but the new members are pretty cool. I also like how you can travel to more worlds, that's definitely a plus.
Also, Can a mod please rename this thread to Mass Effect 2 (spoilers)