Wolf's rain. One of THEE best written anime ever. Splendidly voice-acted even in the English version, for those that may know what I'm talking about, man I wish I had Tsume's voice. Anyway yeah great voice-acting a deep story that required me 3 complete watches to fully understand, but hey I'm a potato so it should take you less, and the most impressive thing about it, while I loved FMA Brotherhood, as that too had splendid English voice-acting also, where do I start? Bradley, Armstrong, Mustang, Scar... ME WANTS THOSE MAGNIFICENT VOICES! , anyway back on topic what bothered me a little is how many times they used silly animations especially in the first half of it.
Wolf's Rain however has not even a single instance when they use silly animations, like characters screaming while growing in size for example, and that really surprised me in an anime. So yeah make some time and check both of these treasures out.